FACTS ABOUT HOW NAD+ CONTRIBUTES TO CELL REGENERATION AND REPAIR REVEALED

7c,d). Inhibition of glycolysis altered neither replication fork progression nor the effects of NAD+ treatment, suggesting that glycolysis will not be a restricting aspect for NAD+-induced effects on DNA synthesis. Phenocopying the effect of BPTES, oligomycin rescued the inhibitory effect of NAD+ treatment on fork velocity partly in HeLa and fully